Gary Anthony Piazza

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ORCID

Inclusion identifies researchers whose recorded research contributions may inform their university’s understanding of its research community. It does not rank individual research quality or establish current employment.

Selected research works

Up to 100 highly cited works; DOI links open the original research. Counts reflect the collected record, not real-time citation totals.

1. Antineoplastic drugs sulindac sulfide and sulfone inhibit cell growth by inducing apoptosis.

   1995 · 428 citations

2. Sulindac sulfone inhibits azoxymethane-induced colon carcinogenesis in rats without reducing prostaglandin levels.

   1997 · 361 citations

3. Apoptosis primarily accounts for the growth-inhibitory properties of sulindac metabolites and involves a mechanism that is independent of cyclooxygenase inhibition, cell cycle arrest, and p53 induction.

   1997 · 351 citations

4. Exisulind induction of apoptosis involves guanosine 3',5'-cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation, and attenuated beta-catenin.

   2000 · 305 citations

5. Honokiol: A Novel Natural Agent for Cancer Prevention and Therapy

   2012 · 232 citations

6. Niclosamide Suppresses Cancer Cell Growth By Inducing Wnt Co-Receptor LRP6 Degradation and Inhibiting the Wnt/β-Catenin Pathway

   2011 · 230 citations

7. The Role of Cyclic Nucleotide Signaling Pathways in Cancer: Targets for Prevention and Treatment

   2014 · 216 citations

8. NSAIDs Inhibit Tumorigenesis, but How?

   2013 · 216 citations

9. Sulfone metabolite of sulindac inhibits mammary carcinogenesis.

   1997 · 208 citations

10. Sulindac derivatives inhibit growth and induce apoptosis in human prostate cancer cell lines

    1999 · 208 citations

11. The path to the clinic: a comprehensive review on direct KRASG12C inhibitors

    2022 · 180 citations

12. Evidence for a role of dipeptidyl peptidase IV in fibronectin-mediated interactions of hepatocytes with extracellular matrix

    1989 · 178 citations

13. An Undesired Effect of Chemotherapy

    2013 · 166 citations

14. Hypoxia-regulated microRNAs in human cancer

    2013 · 164 citations

15. Immunoregulatory Protein B7-H3 Reprograms Glucose Metabolism in Cancer Cells by ROS-Mediated Stabilization of HIF1α

    2016 · 162 citations

16. MiR-181 mediates cell differentiation by interrupting the Lin28 and let-7 feedback circuit

    2011 · 144 citations

17. Cyclic GMP mediates apoptosis induced by sulindac derivatives via activation of c-Jun NH2-terminal kinase 1.

    2000 · 134 citations

18. Sulindac Selectively Inhibits Colon Tumor Cell Growth by Activating the cGMP/PKG Pathway to Suppress Wnt/β-Catenin Signaling

    2013 · 133 citations

19. COX-Independent Mechanisms of Cancer Chemoprevention by Anti-Inflammatory Drugs

    2013 · 132 citations

20. Exisulind (sulindac sulfone) suppresses growth of human prostate cancer in a nude mouse xenograft model by increasing apoptosis

    1999 · 126 citations

21. Exisulind, a novel proapoptotic drug, inhibits rat urinary bladder tumorigenesis.

    2001 · 123 citations

22. Suppression of Wnt/β-catenin signaling inhibits prostate cancer cell proliferation

    2008 · 110 citations

23. Inhibition of PDE5 by Sulindac Sulfide Selectively Induces Apoptosis and Attenuates Oncogenic Wnt/β-Catenin–Mediated Transcription in Human Breast Tumor Cells

    2011 · 106 citations

24. Sulindac Sulfone Induced Regression of Rectal Polyps in Patients with Familial Adenomatous Polyposis

    1999 · 104 citations

25. Exisulind-induced apoptosis in a non-small cell lung cancer orthotopic lung tumor model augments docetaxel treatment and contributes to increased survival.

    2003 · 102 citations

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